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S Dedhar Selected Research

integrin-linked kinase

2/2011A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells.
6/2010Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer.
7/2008Integrin-linked kinase regulates cell proliferation and tumour growth in murine colitis-associated carcinogenesis.
6/2003Characterisation of integrin-linked kinase signalling in sporadic human colon cancer.
2/2002Integrin-linked kinase, a promising cancer therapeutic target: biochemical and biological properties.
10/2001Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.
1/2001Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells.
3/2000Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells.

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S Dedhar Research Topics

Disease

13Neoplasms (Cancer)
11/2017 - 03/2000
6Breast Neoplasms (Breast Cancer)
11/2017 - 10/2000
4Neoplasm Metastasis (Metastasis)
02/2016 - 09/2001
4Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
12/2006 - 01/2001
3Carcinogenesis
07/2008 - 09/2001
3Carcinoma (Carcinomatosis)
09/2001 - 03/2000
2Hypoxia (Hypoxemia)
11/2017 - 10/2013
2Colonic Neoplasms (Colon Cancer)
07/2008 - 06/2003
2Prostatic Neoplasms (Prostate Cancer)
01/2006 - 03/2000
1Colorectal Neoplasms (Colorectal Cancer)
02/2016
1Colitis
07/2008
1Colitis-Associated Neoplasms
07/2008
1Hyperplasia
10/2001
1Polyps
09/2001
1Glioma (Gliomas)
09/2001
1Brain Neoplasms (Brain Tumor)
11/2000

Drug/Important Bio-Agent (IBA)

8integrin-linked kinaseIBA
02/2011 - 03/2000
5Proteins (Proteins, Gene)FDA Link
11/2017 - 01/2001
4beta CateninIBA
09/2001 - 10/2000
2Carbonic Anhydrase IXIBA
11/2017 - 10/2013
2Cyclin D1IBA
07/2008 - 10/2000
2Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
02/2002 - 03/2000
2TCF Transcription FactorsIBA
06/2001 - 10/2000
2Phosphotransferases (Kinase)IBA
11/2000 - 03/2000
1EnzymesIBA
11/2017
1ezrinIBA
02/2016
1CateninsIBA
02/2016
1Biomarkers (Surrogate Marker)IBA
10/2013
1Paclitaxel (Taxol)FDA LinkGeneric
10/2013
1Small Interfering RNA (siRNA)IBA
07/2008
1Fibronectins (Fibronectin)IBA
07/2008
1Glycogen Synthase Kinase 3IBA
12/2006
1Drug CombinationsIBA
09/2006
1Therapeutic UsesIBA
09/2006
1AndrogensIBA
01/2006
1Glycogen Synthase Kinase 3 betaIBA
01/2006
1Glycogen Synthase (Synthase I)IBA
02/2002
1Biological ProductsIBA
02/2002
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
09/2001
1Sulindac (Copal)FDA LinkGeneric
09/2001
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
09/2001
1GelsIBA
09/2001
1Transcription Factors (Transcription Factor)IBA
01/2001
1Cadherins (E-Cadherin)IBA
01/2001

Therapy/Procedure

4Therapeutics
01/2013 - 03/2000
1Drug Therapy (Chemotherapy)
09/2006
1Combination Drug Therapy (Combination Chemotherapy)
09/2006